USE: LDH is an intracellular enzyme found in heart, skeletal muscle, red blood cells, brain, lung, liver and kidney. Increases in value usually indicate cellular death and leakage of the enzyme from cells. A considerable number of conditions can elevate LDH level. Use of Test: A non-specific indicator of disease. Of limited value in supporting the diagnosis of myocardial infarction when testing is performed >48 hours after the onset of chest pain. Maybe useful occasionally in the assessment of patients with liver disease or malignancy (especially lymphoma, seminoma, hepatic metastases); anaemia when haemolysis or ineffective erythropoeisis is suspected.